With the increase in the humidity level and pain of having to force yourself on a repetitive exercise, Imagine if, you could have the benefits of exercise without any of the effort. That scenario isn’t a ridiculous fantasy but a serious scientific goal, and researchers have recently created a blueprint of the molecular reactions to exercise.
Researchers from the University of Sydney and the University of Copenhagen worked together on the study, which used a technique called mass spectrometry to study the protein changes in skeletal muscle after exercise.
The findings, published in Cell Metabolism on Oct. 2, show that exercise causes 1,000 molecular changes in skeletal muscles.
Four healthy males had a muscle biopsy before exercise, then rode an exercise bicycle as hard as they could for 10 minutes, and finally gave a second sample of muscle. Their samples were shipped to Sydney, where they were examined.
The blueprint is incredibly complicated, and because no single drug could safely deliver 1,000 effects, the researchers will have to identify the most significant biological changes before they can start to create a drug. They plan to create an exercise blueprint for diseased individuals, to identify the important differences from healthy people.
An exercise drug could have major benefits for the elderly, as well as people who have obesity, type-2 diabetes, and cardiovascular disease. Though it sounds like a gift to the lazy, such a treatment could transform the lives of many who cannot exercise.
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